Immunoregulatory profiles in liver transplant recipients on different immunosuppressive agents
نویسندگان
چکیده
منابع مشابه
Notes on Some Immunosuppressive Agents and Their Use in Human Liver Transplant Recipients
Cyclophosphamide has long been known to be an extremely effective immunosuppressant in rodents. In humans, the drug has been used extensively for cancer chemotherapy and for the treatment of autoimmune disorders. Several years ago cyclophosphamide was introduced by Santos and his associates into to the field of clinical bone marrow grafting. There are probably tho reasons why cyclophosphamide h...
متن کاملClinical Pharmacokinetics of Tacrolimus in Iranian Liver Transplant Recipients
Tacrolimus, a cornerstone of immunosuppressive therapy in solid organ transplantation, has a narrow therapeutic range with considerable inter-individual and intra-individual pharmacokinetic variability. To date, there is no information on the pharmacokinetics of tacrolimus in Iranian liver transplant recipients. This study was designed to determine pharmacokinetic properties of orally administe...
متن کاملClinical Pharmacokinetics of Tacrolimus in Iranian Liver Transplant Recipients
Tacrolimus, a cornerstone of immunosuppressive therapy in solid organ transplantation, has a narrow therapeutic range with considerable inter-individual and intra-individual pharmacokinetic variability. To date, there is no information on the pharmacokinetics of tacrolimus in Iranian liver transplant recipients. This study was designed to determine pharmacokinetic properties of orally administe...
متن کاملFever in liver transplant recipients: changing spectrum of etiologic agents.
Febrile episodes in liver transplants were prospectively evaluated. Fever was due to infections in 78% of the episodes (35 of 45) and due to noninfectious causes in 22% (10 of 45). The predominant sources of fever were bacterial infections (62%; 28 of 45) and viral infections (6%; 7 of 45), whereas rejection accounted for only 4% of the episodes (2 of 45). Forty percent of the infections were u...
متن کاملTuberculosis in renal transplant recipients on various immunosuppressive regimens.
BACKGROUND Mycophenolate mofetil (MMF) and tacrolimus (TAC) are more potent than conventional immunosuppressive drugs, i.e. azathioprine, cyclosporin and prednisolone, and may be associated with an increase in the incidence of infections in the post-transplantation (post-tx) period. The aim of this study was to determine if the use of either or both of MMF and TAC for immunosuppression in renal...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Human Immunology
سال: 2009
ISSN: 0198-8859
DOI: 10.1016/j.humimm.2008.12.008